Cosme Pharma


 PRODUCTS

 
Sr. No. Product Strenght & Composition Packing
(1) Cosklot Injection Etamsylate Injection
Preventing Blood Loss
1 Box X 5 AMP
(2) Jectocos Plus Injection Parenteral Iron Therapy
Non-sorbitol-citric acid
complex + Folic acid +
Hydroxycobalamin for
IM ini
1 Box X 5 AMP
(3) Cosvate Cream Clobetasol Propionate
BP 0.05% 
1 Tubes X 10
(4) Cosvate -G Cream Clobetasol Propionate
BP 0.05% Gentamicin 0.1 % 
1 Tubes X 10
(5) Cosvate -GM Cream Clobetasol Propionate
BP 0.05% Gentamicin 0.1 %  Miconazole Nitrate BP 2%
1 Tubes X 10
(6) Pernex AC 2.5% Gel Hydrous Benzoyl Peroxide BP, Anhydrous Benzoyl Peroxide 2.5% 1 Tubes X 10
(7) Pernex AC 5% Gel Hydrous Benzoyl Peroxide BP, Anhydrous Benzoyl Peroxide 5% 1 Tubes X 10
(8) Futop Ointment Sodium Fusidate BP 20 mg 1 Tubes X 10
(9) Cosklot 250 Tablet Etamsylate 250mg Tablets Preventing Blood Loss 1 Box X 10 
(10) Cosklot 500 Tablet Etamsylate 500mg Tablets Preventing Blood Loss 1 Box X 10 
(11) Movelisin Gel Flufenamic Acid 30gm + Salicylic + MPS
The Transparent Pain
Reliever
1 Tubes X 10
(12) Feros I.V Injection Each ml contains Ferric Hydroxide in complex with Sucrose eq. to elemental Iron 20mg  Amber glass ampoule of 2.5ml X5 & 5 ml  X 5 in a tray in a carton box.
(13) Rovate Lotion Betamethasone Dipropionate USP equivalent to Betamethasone 0.05% w/y. Plastic Bottle of 30ml X 1 in a carton Box
(14) Flucos Lotion Fluconazole USP 2% w/y, Zinc Pyrithione (ZPTO) 1% w/y. Plastic Bottle of 30ml X 1 in a carton Box
(15) Ondace Injection    
(16) Jectocos Injection Each ml contains Iron Sorbitol Citric Acid Complex corresponding to fe (total) 50mg.  

 

   Cosklot

(Etamsylate 250/500 mg tabl & 2ml inj,)

 

Unique mode of Action:

1. Platelet Plug formation. Enhances Platelet response to Thromboxane A2 promotes platelet aggregation & adhesiveness

2. Fibrin Formation. Increases availability of Thromboplastin converts Prothrombin to Thrombin

3. Restores Capillary resistance. Inhibits Hyaluronidase/Enhances Polymerization of Hyaluronic Acid / Improves vascular tone4. Prevents vasodilatationNo risk of Deep vein thrombosis. No hormonal side effects. No drug interaction.


Indications:

Primary Menorrhagia

Puberty Menorrhagia

IUCD Induced Menorrhagia

Myoma Bleeding

Dysfunctional Uterine Bleeding (DUB)

Post abortion or post-partum haemorrhage

Oral contrcptive induced bleeding

Post-surgical haemorrhagic disorder

Epistaxis

Haemoptysis

Haematemesis

Bleeding piles / Melaena

Peri-Ventricular Haemorrhage (PVH)

 

Contra-indication:

Patients hypersensitive to Etamsylate or with previous history of Thrombocytopenia Purpura or Haemophillia.

 

   Pernex-AC

(Benzoyl Peroxide + Acrylates Copolymer Complex)

How acrylates Copolymer Complex works:

1. Beads come in contact with sebum

2. Absorbs sebum

3. Forces glycerin out of the skin surface

 

   Cosvate

(Clobetasol Propionate Cream 0.05% w/w)

Active ingredient: Clobetasol 0.05% w/w

Preservative: Cjorocresol 0.1% w/w

 

Penetration enhancer emollient base:

Isopropyl Myristate 8% w/w, Ceromacragol 3% w/w, and Glycerine 5% w/w

In dermatitis, eczema, and lichen planus, use Cosvate.

In dermatitis complicated with bacterial infection, use Cosvate-G.

In dermatitis complicated with bacterial & fungal infections, use Cosvate-GM

 

   Movelisin Gel

(Flufenamic acid 30mg + Salicylic Acid 20mg + Mucopolysaccharide Polysulphate 2mg)

 

Salicylic Acid:

Ideal Muscle Relaxant

1. Pronounced anti-inflammatory and analgesic effect

2. Improves microcirculation at affected site

3. Relieves muscles spasm

 

Flufenamic acid:

The powerful NSAID

1. Inhibits the synthesis of prostaglandins

2. Inhibits the release of Iysosomal enzyme

 

Mucopolysaccharide Polysulphate(MPS):

One & only anti-edematous

1. Promotes renewed formation of proteoglycans & collagen

2. Increase synthesis of hyaluronic acid

 

   Futop cream/ointment

(Fusidic acid/sodium fusidate 2% w/w)

1. Cosmitically acceptable for facial use & thin delicate areas

2. Convenient for use in groins & armpits

3. Excellent penetration through intact skin as well as crust

4. Superior to Povidone Iodine & 1st choice for treatment of impetigo

5. 98% cure rates in Pyoderma, Impetigo, and Carbunles

 

For treatment of bacterial skin infecions:

1. Folliculitis

2. Pyoderma

3. Furuncles

4. Impetigo

 

   Jactocose

(Iron-sorbitol-citric acid complex for IM inj.)

Dose

For the use of a Registered Medical Practitioner or a Hospital or a Laboratory only

         1.5 mg per kg body weight

         For adults. additional 5-7 ampoules are recommended

         3 ampoules will lead to an increase in Hb levels of approx. 1gm%

Administration

         Deep intra-muscular injection lobe administered in the upper quadrant of the gluteal muscles by Z-track technique

Indications:

         Patients unable to tolerate or unwilling to take adequate doses of iron orally.

         Patients unable to absorb adequate doses of iron orally.

         Patients who need rapid normalization of haemoglobin values but for whom blood transfusions are undesirable or unsuitable.

         Patients with chronic bleeding in whom a positive iron balance cannot be obtained by oral administration.

          Patients with gastrointestinal bleeding where oral iron therapy mask melena.

         Late pregnancy where satisfactory Hb levels may not be attained with orally administered iron.

When compared with other Iron preparation, Jectodos is to be preferred, being easy to administer and causing no unpleasant effects at the injection site.

Jectocos may cause localized or generalized urticaria. Jectocos is non-antigenic and this reaction is in no way similar i to the anaphyllactoid reactions reported with other parenteral iron complexes. Urticaria is probably the result of histamine liberation from mast cell de-granulation.

A test dose of 0.5 ml of Jectocos injection has to be injected deep i.m. Patients are to be observed for any signs or symptoms of allergy for 24 hours.

Smaller the better

 Low molecular weight - 3400 Daltons

Efficacy

         60% of iron gets rapidly absorbed directly into the blood stream (caplillary absorption). Complete saturation of transferrin within 6 hours.

         Immediate availability for haematopoiesis and rapid utilization by bone marrow.

         Faster rise in Hb levels (reticulocyte response occurs within 6 days)

         Administration of one ampoule alternet day leads to an increase in Hb levels of approx. 2 gm%within 10 days

Safety

         Serum iron concentration reaches a maximum within 2 hours and gets normalized again within 24 hours

         Pattern of absorption and clearance is maintained from day to day even when repeated daily injections are administered.

         Rapidly excreted in the urine with no impairment of kidney functions.

Tolerability

         70-80% of iron gets absorbed in 3 hours and almost 100% within 10 days

         Complete removal from the injection site

 

 

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